Kamagra is an oral drug for the treatment of erectile dysfunction. It contains 100 mg of Sildenafil. With sexual excitement, the drug restores reduced erectile function by increasing blood flow to the penis. The physiological mechanism contributes to an erection, including the release of nitric oxide (NO) in the corpora cavernosa during sexual excitement. The released nitric oxide activates the enzyme guanylate cyclase, which stimulates an increase in the level of cyclic guanosine monophosphate (cGMP), which, in turn, causes relaxation of the smooth muscles of the corpora cavernosa, promoting blood flow.
When to use the drug?
This drug is used for erectile dysfunction, characterized by an inability to achieve or maintain an erection sufficient for satisfactory intercourse. Kamagra is effective only when there is sexual stimulation.
What is the dosage regimen of Kamagra?
To avoid complications, use this ED drug strictly as directed by your doctor. This pills should be taken approximately one hour before the planned sexual intercourse. The recommended dose of the drug is 50 mg and is taken before meals.
Considering the effectiveness and tolerability of this drug, its dosage can be increased to 100 mg or reduced to 25 mg.
The maximum recommended dose of the drug is 100 mg. The maximum recommended frequency of drug intake is 1 time per day.
How to take the medicine if you have hepatic impairment?
Since sildenafil clearance is reduced in patients with hepatic impairment (eg cirrhosis), the recommended dose is 25 mg. Depending on the drug effectiveness and tolerability, if necessary, the dose can be increased gradually to 50 mg and 100 mg. If patients are taking Kamagra with CYP3A4 inhibitors, an initial dose of 25 mg should be taken. In order to minimize the possible development of postural hypotension in patients taking α-adrenoceptor blockers, their condition should be stabilized with α-adrenoceptor blockers prior to starting sildenafil. An initial dose of 25 mg should be considered.
These tablets act on the body for a much longer period than any other drugs. This promotes more prolonged sexual intercourse. Besides, Kamagra can be mixed with alcohol. For example, Viagra is not recommended to be taken together with alcohol, and its effect on the body ends faster.
How to take this ED drug correctly?
Kamagra should be taken before intercourse for about an hour. Before taking these pills, you need to read the instructions to make sure that you have no contraindications and allergies to the components of the pills. The dose should be 50 mg per day, but doubling is allowed if the form of erectile dysfunction is severe.
Regular use of this medication provides an improvement in sexual intercourse. The duration increases, but the quality does not suffer, and even becomes even better. The effect of pills occurs only with sexual stimulation and excitement.
Kamagra vs Viagra
The drugs, as indicated above, are based on the action of sildenafil. For this reason, Kamagra is often considered as an alternative to Viagra, which has millions of satisfied users around the world. Initially, the pharmaceutical concern Pfizer was the sole owner of the rights to release tablets with the same formula as Viagra has. But when the license expired, everyone could start producing the drug according to the original formula. Therefore, Viagra now has a number of analogs:
- Oral Jelly Sildeafil;
- Super Sildenafil;
- Viagra Professional;
- Viagra Soft.
The difference between Viagra and Kamagra is minimal, since the drugs are developed within a single formula. At the same time, the described drug price is cheaper, since people do not have to pay for the promoted Pfizer brand. All generics of Viagra receive a more attractive cost, although in the effectiveness they often surpass the original product.
How long does the effect last?
The advantage of taking the drug is that its effect on the body is 2 times faster. At the same time, the duration of the effect reaches 5 hours, during which a man obtains a persistent erection. The dosage of the drug is 100 mg.
What are the possible side effects?
- Very often: headache
- Often: dizziness, color distortion of vision (chloropsia, chromatopsia, cyanopsia, erythropsia, xanthopsia), visual impairment, blurred vision- hyperemia, hot flashes, nasal congestion, dyspepsia, nausea.
- Infrequently: rhinitis, hypersensitivity, drowsiness, hypesthesia- disorders associated with lacrimation (dry eyes, dysfunction of the lacrimal gland, increased lacrimation), eye pain, photophobia, photopsia, redness of the eye vessels, brightness of visual perception, conjunctivitis, spatial disorientation (vertigo), tinnitus, tachycardia, palpitations, arterial hypertension, arterial hypotension, nosebleeds, congestion of the paranasal sinuses, pain in the upper abdomen, gastroesophageal reflux disease, vomiting, dry mouth, rash, myalgia, pain in the limbs, hematuria, chest pain, increased fatigue, hot flushes, increased heart rate.
- Seldom: acute disturbance of cerebral circulation, transient ischemic attack, seizure, fainting, anterior non-arteritic ischemic neuropathy of the optic nerve, retinal vascular occlusion, retinal hemorrhage, arteriosclerotic retinopathy, retinal disease, glaucoma, visual field defect, diplopia, decreased visual acuity, myopia, asthenopia, floating opacities of the vitreous membrane, disease of the iris, iridescent circles in the field of vision, eye swelling, eye swelling, visual disturbances, conjunctival hyperemia, eye irritation, unusual sensation in the eye, eyelid edema, discoloration of the sclera, deafness, sudden cardiac death, myocardial infarction, ventricular arrhythmia, atrial fibrillation, unstable angina- a feeling of tightness in the throat, swelling of the nose, dryness of the nasal mucosa, oral hypesthesia, Stevens-Johnson syndrome, toxic epidermal necrolysis, penile bleeding, hematospermia, priapism, irritability.
Reporting suspected adverse reactions
Reporting information on suspected adverse reactions identified after registration of a medicinal product is of great importance. This allows medical specialists to continue monitoring the balance of benefits and risks of the drug. Healthcare professionals and patients are asked to report any adverse reactions to the healthcare institutions.
What should I tell my doctor before taking this medicine?
- Hypersensitivity to any drug component;
- Simultaneous administration of drugs that are donors of nitric oxide (amyl nitrite) or nitrates in any form;
- Simultaneous reception with guanylate cyclase stimulants (riociguat);
- Severe liver failure;
- Hereditary degenerative diseases of the retina (for example, hereditary retinitis pigmentosa;
- Loss of vision in one eye due to anterior non-arteritic ischemic neuropathy of the optic nerve, regardless of whether this episode was associated with previous use of a PDE-5 inhibitor or not;
- Arterial hypotension;
- Severe cardiovascular disease (eg, severe heart failure, unstable angina);
- Myocardial infarction transferred in the last 6 months;
- A stroke suffered in the last 6 months;concomitant use with inhibitors of the isoenzyme CYP3A4 (for example, ketoconazole, itraconazole, ritonavir, erythromycin, saquinavir, clarithromycin);
- Concomitant use of drugs for the treatment of pulmonary arterial hypertension and drugs containing sildenafil or any other PDE-5 inhibitor;
- Men with rare hereditary galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption syndrome;
- Concomitant use with other oral or topical agents for the treatment of erectile dysfunction.
Can Kamagra cause overdose?
Yes, it can. When taking high doses of the drug, there may be an increase in side effects observed when taking the recommended doses. In case of overdose, general symptomatic and supportive treatment is prescribed.
Questions to doctors
A man who faces the problem of insufficient erection should take timely measures to correct the situation. At the same time, he should study in detail all aspects of taking medications in order to find the best option for himself. So, patients usually ask such questions when they plan to take sildenafil.
Question: Is this drug capable of harming men over 50?
Answer: the funds, which are based on sildenafil, can be used by people up to 65 years old. If the patient’s age exceeds the specified limit, then the appointment can be prescribed only after consultation with a specialist. The drug can be used by men over 50 without fear. The only exceptions are cases when a person has contraindications that do not allow using this drug.
Question: how much does this ED drug cost?
Answer: It is difficult to answer such a question, since various retail stores set their own pricing policy. The price for this drug is considerable lower in comparison with a brand-name drug.
Question: can women take this sildenafil-based drug?
Answer: No, they can’t. The drug is specially designed for male patients. For the needs of girls, there are separate drugs called Female Viagra. It should be taken before sex as male analogs.
Question: Can Kamagra pill be divided?
Answer: Yes, it is possible to devide the drug before taking. This is especially worth doing in the case when the use of pills occurs for the first time, and the male body has not yet had time to adapt to the drug effects.
Question: Are these tablets used prophylactically to fight impotence?
Answer: Yes, they are. This drug can help cope with such disorders, but it should be used only after consulting a specialist. If the potency is in a normal state, then the remedy should be used no more than 3 times a week.