rhinocortRhinocort contains the active ingredient Budesonide, which belongs to the group of so-called corticosteroids. Budesonide has anti-inflammatory effects. It is used to treat seasonal and perennial allergic and non-allergic rhinitis, hayfever and non-allergic rhinitis. It is also used to treat nasal polyps, as well as to prevent recurrence after surgical removal of nasal polyps.

In what cases to use this drug?

For inhalation use: bronchial asthma of mild, moderate and severe course, treatment of chronic obstructive pulmonary disease (COPD).

For oral administration: remission induction in patients with exacerbation of mild and moderate forms of Crohn’s disease with lesions of the ileum and/or ascending colon; remission induction in patients with active collagenous colitis.

How should I use Rhinocort?

Before using for the first time, it is recommended to read the instruction for use and carefully follow the instructions.

Rhinitis

  • Usually the following dosage is used for adults, elderly patients and adolescents over 12 years of age: 2 Inhalations 100 mg in the morning in each nostril (400 mcg per day).
  • As soon as you notice an improvement in your discomfort, your doctor can reduce the dose of inhalations in the morning in each nostril (200 mcg / day).

Treatment and prevention of nasal polyps

  • Usually, in the morning and evening, 1 Inhalation 100 in each nostril (400 mcg per day).
  • Do not change from prescribed dosage. If you think the medicine is too weak or too strong, talk to your doctor or pharmacist.

What side effects are caused by this medicine?

  • The part of the skin: allergic exanthema, striae rubrae, petechia, ecchymosis, steroid acne, delayed wound healing, contact dermatitis.
  • The musculoskeletal system: aseptic bone necrosis (femur and humerus head).
  • The organs of vision: glaucoma, cataracts.
  • Mental disorders: depressive syndrome, irritability, euphoria.
  • The digestive system: discomfort in the stomach, duodenal ulcer, pancreatitis.
  • The endocrine system: Cushing’s syndrome, moon face, corp obesity, decreased glucose tolerance, diabetes mellitus, insufficient adrenal cortex function, growth retardation in children, impaired secretion of sex hormones (for example, amenorrhea, hirsutism, impotence).
  • The side of metabolism: sodium retention with the formation of edema, increased excretion of potassium.
  • The cardiovascular system: arterial hypertension, increased risk of thrombosis, vasculitis (withdrawal syndrome after long-term therapy).
  • The immune system: impaired immune response (for example, increased risk of infections).

When is this drug contraindicated?

  • Hypersensitivity to budesonide.
  • The inhalation use: children under 6 years of age.

Take this inhalation drug with caution in the following cases:

  • tuberculosis;
  • fungal, bacterial and viral infections of the respiratory system;
  • cirrhosis of the liver;
  • glaucoma;
  • hypothyroidism;
  • osteoporosis.

Oral administration: cirrhosis of the liver; children under 18 years of age.

Take this medicine with caution in the following diagnosis:

  • tuberculosis;
  • arterial hypertension;
  • diabetes mellitus;
  • osteoporosis;
  • gastric ulcer and duodenal ulcer;
  • glaucoma;
  • cataracts;
  • family history of diabetes or glaucoma;
  • pregnancy.

Rhinocort during pregnancy and lactation

The use during pregnancy is possible when the intended benefit to the mother outweighs the potential risk to the fetus. If the use during lactation is necessary, a woman should stop breastfeeding.

With what medications it can be combined?

Cimetidine and omeprazole do not have a clinically significant effect on the pharmacokinetic parameters of budesonide when taken orally. However, under the influence of cimetidine, it is possible to slow down the hepatic metabolism of budesonide.

Budesonide is characterized by lower systemic bioavailability compared to other GCS, therefore, drug interactions may be less pronounced compared to many other drugs in this class.

The risk of drug interactions may be increased in the elderly and in patients with impaired renal or hepatic function.

Overdose

With acute overdose of Rhinocort, clinical manifestations do not occur. With prolonged use of the drug in doses significantly higher than recommended, a systemic glucocorticosteroid effect in the form of hypercortisolism and suppression of adrenal function may be recorded.