Biomedical Computation


BINANA (BINding ANAlyzer) is a novel Python-implemented computer algorithm for analyzing ligand binding. The program identifies key binding characteristics like hydrogen bonds, salt bridges, and pi interactions.

BINANA analyzes the geometries of predicted ligand poses to identify molecular interactions that contribute to binding. It is very useful because accurately characterizing these interactions allows medicinal chemists and structural biologists to assess whether a predicted ligand merits further study.